I am looking to record my desktop in high quality (not nearly as lossy as H.264). I have tried OBS @ 200mbps and nVidia Shadowplay @ 50mbps and the text on my desktop is still noticibly blurry when i view the video I just recorded at the native resolution it was recorded at. OBS is a little bit better than nVidia.
Try lossless encoding with ffmpeg
First, with YUV444P
ffmpeg -f gdigrab -framerate 60 -i desktop -crf 0 -pix_fmt yuv444p -preset ultrafast yuv-cap.mp4
If not clear enough,
ffmpeg -f gdigrab -framerate 60 -i desktop -c:v libx264rgb -crf 0 -pix_fmt bgra -preset ultrafast rgb-cap.mp4
These will likely not be compatible with most video editors, but if the result is satisfactory, then you can transcode at leisure to a compatible codec like PNG in MOV..etc
You can add
-draw_mouse 0 before
-i desktop to skip recording the cursor.