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Well going by the numbers h264 has a lesser bit-depth and color accuracy than ProRes 422. PR422 has 10bit and 4:2:2 chroma sub-sampling, h264 has 8bit and 4:2:0 unless you encode in the Hi422P Intra profile which isn't very well supported in the wild but offers 10bit and 4:2:2. So in that case I don't think you will have any difference what so ever between ...

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